Produkty dla api farmaceutyczna (30)

Enzalutamide binds to androgen receptors and thereby inhibits them (antiandrogen). In addition, translocation in the cell nuclei is inhibited and the binding to the DNA is weakened, as well as the recruitment of cofactors for transcription. This leads to the inhibition of gene expression, which are regulated by the androgen receptors. Due to the triple mechanism of action, Enzalutamide differs from the usual anti-androgenic substances. Due to its anti-androgenic properties, the active ingredient also has an antineoplastic effect in androgen-sensitive tumors (e.g. metastatic prostate cancer). Name:Enzalutamide CAS Number:915087-33-1 Indication:prostate cancer Type:antiaandrogen

CAS: 53714-56-0 Molecular Weight: 1209.4 Chemical Formula: C59H84N16O12 Drug substance / API: EU CEP certificate ready.

This industry requires careful selection of materials – purity is essential, as is the chemical nature of the products used. For example, polyisoprene rubber (IR) is used in applications due to the proteins present in natural rubber (NR). There are many impurities in general rubber compounding ingredients that must be avoided for use in these applications. Medical applications require some products to undergo stringent cleaning regimes together with repeated steam sterilisation. When developing the rubber compound and part design, these considerations are taken into account – resistance to steam and cleaning products is essential.

AOPB est autonome pour la fabrication des moules : - moules classiques, - moules 3 plaques, - moules à dévissage, - moules à canaux chauds, - moules de surmoulage d'inserts, - moules à versions.

Unser Leistungsangebot umfasst die Entwicklung und Lohnfertigung pulverförmiger Nahrungsergänzungsmittel.  Wir bieten neben der Private Label Abfüllung auch die Neuentwicklung eigener Rezepturen.

•Choosing a suitable manufacturer •Designing packaging and labelling Having received the chemical formula of the future product, we select the best suitable plant for its production Criterias key include: •production facilities so that there are no delays in terms of delivery; •suppliers – in order to always have the best ingredients; •storage conditions – so that your product reaches the consumer in its original form. We also prefer enterprises that participate in environmental programs, helping to preserve nature. Thus, we will make sure that your products are of the highest quality and competitive in the market.

High-performance reactor systems for API synthesis, small scale production and pilot plant applications Glass, glass-lined steel reactor: 15, 30, 60, 100, 160, 250 liter Pressure: -1.0 (FV) to +0.5 bar Temperature: -60 °C (-90 °C) to +200 °C Material: Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, tantalum A clean-room setup and other materials are available to meet your specific process requirements. Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems: The inert materials allow safe processing in a inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. The system consists of:

Clofazimin wird zu den kationischen, amphiphilen Arzneimitteln gezählt. Der Wirkmechanismus ist nicht vollständig geklärt. Clofazimin ist ein roter Farbstoff, der einen bakteriostatischen Effekt auf das Lepra-verursachende Mykobakterium leprae hat. Der Wirkstoff wird von der WHO zur Therapie von Lepra verwendet. Name:Clofazimin CAS:2030-63-9 Indikation:Antimycobakteriell (Lepra)

Clofazimin is considered one of the cationic amphiphic medicines. The mechanism of action is not fully understood. Clofamizin is a red dye that has a bacteriostatic effect on the leprosy causing mycobacterium leprae. The active ingredient is used by WHO to treat leprosy. Name:Clofazimine CAS:2030-63-9 Indication:Antimycobacterial

Clofazimina es considerada como una de las medicinas antimicrobianas. En combinación con otras medicinas se usa contra la efermedad lepra. El mecanismo detras de su función sigue siendo sujeto de investigación. Nombre:Clofazimina Número-CAS:2030-63-9 Indicación:Lepra

El lactato de etacridina es un compuesto orgánico aromático basado en la acridina. Se utiliza principalmente como antiséptico (en forma de pomadas y soluciones) para el tratamiento de heridas infectadas y piodermas. Además, se aplica como solución de irrigación vesical y vaginal. Es eficaz contra la mayoría de las bacterias grampositivas, como los estreptococos y los estafilococos, pero ineficaz contra las bacterias gramnegativas, como Pseudomonas aeruginosa. Además, el lactato de etacridina se utiliza para la diarrea (o la profilaxis de la diarrea). En este caso, el principio activo normaliza el aumento del movimiento de los intestinos gracias a su efecto antiespasmódico. También tiene un efecto antibacteriano y reduce la permeabilidad de la pared intestinal a los fluidos. De este modo, se puede contrarrestar la diarrea. Por regla general, se administra en combinación con albuminato de tanino. Nombre:Lactato de etacridina monohidratado Número CAS:6402-23-9 Indicación:Antiséptico y antibacteriano

Ethacridine lactate is an aromatic organic compound based on acridine. It is mainly used as an antiseptic (in the form of ointments and solutions) for the treatment of infected wounds and pyoderma. Besides, it finds application as bladder and vaginal irrigation solution. It is effective against most gram-positive bacteria, such as streptococci and staphylococci, but ineffective against gram-negative bacteria, such as Pseudomonas aeruginosa. In addition, ethacridine lactate is used for diarrhea (or diarrhea prophylaxis). Here, the active ingredient normalizes the increased movement of the intestines through its antispasmodic effect. It also has an antibacterial effect and reduces the permeability of the intestinal wall to fluids. Thus, diarrhea can be counteracted. As a rule, it is administered in combination with tannin albuminate. Name:Ethacridine lactate monohydrate CAS Number:6402-23-9 Indication:Antiseptic & Antibacterial

Crotamiton is an active pharmaceutical ingredient produced under cGMP. * only European manufacturer * competitive process * up-to-date documentation * starting materials sourced from EU (no dependence on China) Crotamitone is an antipruriginosum used to treat burial mites (scabies). It works against the mites themselves, but also against the itching. CAS:483-63-6 Product Information:API Indication:Scabicidal and antipuritic Dosage:liquid Route of Synthesis:Synthetic Loss of Exclusivity:expired in EU, US

Warfarin Sodium, amorphous is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads [129-06-6]. It is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions. Detailed specification, Certificate of Analysis and samples are available on request. Warfarin sodium is a 4-hydroxycumarin, these are known as vitamin K antagonists. Vitamin K antagonists are anticoagulants that encroach on the blood clotting cascade. Since the substance can have significant fluctuations in its effectiveness, depending on the genotype, the blood clotting levels for dose tuning should be tested regularly. CAS:129-06-6 Product Information:API Route of Synthesis:Synthetic Patent Expiry:EU, US - expired Indication:Anticoagulant, Tromboembosism Dosage:Oral and iv formulation

El ácido metansulfónico pertenece al grupo de los ácidos metansulfónicos. El intermediario se utiliza en las industrias farmacéutica (y veterinaria), agrícola y de fragancias. Se aplica en la producción de APIs en forma de sal de mesilato. Nombre:Ácido metansulfónico Sinónimo:MSA CAS:75-75-2 Aplicación:APIs en forma de sal de mesilato Uso:Agro, fine chem, perfume, farma, vet

Ethacridinlactat ist eine aromatische organische Verbindung auf der Basis von Acridin. Es wird hauptsächlich als Antiseptikum (in Form von Salben und Lösungen) zur Behandlung infizierter Wunden und Pyodermien verwendet. Daneben findet es Anwendung als Blasen- und Vaginalspüllösung. Es ist wirksam gegen die meisten grampositiven Bakterien, wie Streptokokken und Staphylokokken, aber unwirksam gegen gramnegative Bakterien wie Pseudomonas aeruginosa. Darüber hinaus wird Ethacridinlactat bei Durchfall (bzw. zur Durchfallprophylaxe) angewandt. Hierbei normalisiert der Wirkstoff durch seine krampflösende Wirkung die gesteigerte Bewegung des Darmes. Es ist zudem antibakteriell wirksam und senkt die Durchlässigkeit der Darmwand für Flüssigkeiten. So kann einem Durchfall entgegengewirkt werden. Im Regelfall wird es in Kombination mit Tannin-Albuminat verabreicht. Name:Ethacridinlactat-Monohydrat CAS Nummer:6402-23-9 Indikation:Antiseptikum antibakteriell

Methansulfonsäure gehört zur Gruppe der Methansulfonsäuren. Das Zwischenprodukt wird in der Pharma, Agro und Parfümindustrie verwendet. Es wird auch bei der Herstellung von APIs in Mesilatsalzform verwendet. Name:Methansulfonsäure Synonym:MSA CAS Nummer:75-75-2 API Anwendung:Mesilate-API Salze Verwendung:Agrar, Elektro, Feinchem, Pharma, Vet

Zofenopril calcium is an inhibitor of the angiotensin-converting enzyme (ACE inhibitor). Angiotensin I & II control the tone of the blood vessels and are part of the Renin Angiotensin aldosterone system. The increase in angiotensin II leads to a reduction in vascular tone, which leads to lower blood pressure. Therefore, it is used in the therapy of arterial hypertension and acute heart attacks. Name:Zofenopril Calcium CAS Number:81938-43-4 Indication:Hypertension

Propofol belongs to the group of phenol derivatives. The active substance is a short-acting anesthetic. It is used for the initiation and maintenance of intravenous anesthesia. Name:Propofol CAS Number:2078-54-8 Indication:Anesthesia, sedation

Ketoprofen is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, JP monographs. Its CAS-N° reads 22071-15-4. It is used in treatment of arthritis-related inflammatory pains, severe toothaches that result in the inflammation of the gums or nerve pain. Ketoprofen is an acidic, non-opioid analgesic used for pain and inflammation. By inhibiting prostaglandin synthesis at the key enzyme cyclooxygenase, it can be used for acute and chronic pain (e.g. arthrosis and arthritides). Like most active ingredients in its class, it is poorly tolerated by the gastrointestinal tract, a particular side effect is light sensitization. Detailed specification, Certificate of Analysis and samples are available on request. CAS:22071-15-4 Product Information:API Route of Synthesis:Synthetic Patent Expiry:EU, US - expired Indication:Analgesic, Anti-inflammatory Dosage:Oral Name:Ketoprofen

Diethylpropion hydrochloride is an amphetamine derivative that acts systemically on the cardiovascular system, certain organs and the brain (or CNS) as an indirect α-sympathomimetic. It is counted among the psychostimulants and suppresses needs such as sleep, appetite, thirst and urination. The release of catecholamines (e.g. adrenaline, dopamine) increases heart rate, blood pressure and pulmonary circulation. It is used to treat obesity. CAS:134-80-5 Product Information:BTM, contr. substance US schedule IV Route of Synthesis:Synthetic Patent Expiry:EU, US - expired Indication:Antipsychotic, CNS Stimulant,Anorexic Dosage:oral grade specialities Name:Diethylpropione hydrochloride

Doxazosin Mesylate is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads 77883-43-3. It is used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia - BPH. Doxazosin mesylate is a selective α-blocker that selectively binds to α1-receptors, thus dilating peripheral blood vessels. This reduces blood pressure and cholesterol levels of the serum. Detailed specification, Certificate of Analysis and samples are available on request. CAS:77883-43-3 Product Information:API Route of Synthesis:Synthetic Patent Expiry:EU, US - expired Indication:Antihypertensive, Adrenergic Blocker Dosage:Oral formulation

ASMF: Ganirelix, Atosiban,Terlipressin CEP: Leuprorelin, Desmopressin, Oxytocin, Octreotide US DMF: Eptifibitide, Liraglutide, Ganirelix, Glatiramer, Desmopressin, LInaclotide, Nesiritide, Teriparatide. R&D: Semaglutide, Degarelix, Goserelin, Ziconotide etc.

CAS: 147245-92-9 Formula: C25H45N5O13

US DMF + KDMF+ WC CAS: 16679-58-6 Formula: C46H64N14O12S2

CAS: 123246-29-7 Molecular Weight: 1570.32 Chemical Formula: C80H113ClN18O13 Drug substance / API: US DMF (30800) ready; EU ASFM ready; EU WC certificate.

For the symptomatic treatment of moderate to severe irritable-bowel syndrome with constipation (IBS-C) in adults

CAS: 910463-68-2 Formula: C187H291N45O59 Molecular Weight: 4113.58Da

Glass pilot reactor and pilot plant Glass reactor: 15, 30, 60 liter Pressure: -1.0 (FV) to +0.5 bar Temperature: -60 °C (-90 °C) to +200 °C Material: Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, tantalum A clean-room setup and other materials are available to meet your specific process requirements. Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems. The inert materials allow safe processing in an inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. The system consists of: Reactor, solid jacketed full view glass reactor to easily improve and control chemical reactions by visual observation Distillation glass overhead built with buchiflex components (unique flexible ball - socket joints) for mulitple, reliable processes under full vacuum Glass reactor: 15, 30, 60 liter Pressure:-1.0 (FV) to +0.5 bar Temperature:-60 °C (-90 °C) to +200 °C

Basic glass reactor systems for API synthesis, small scale production and pilot plant. Glass reactor: 15, 30, 60 liter Pressure: -1.0 (FV) to +0.5 bar Temperature: -60 °C (-90 °C) to +200 °C Material: Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, Tantalum A clean-room setup and other materials are available to meet your specific process requirements. Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems. The inert materials allow safe processing in an inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. The system consists of: Solid jacketed full view glass reactor to easily improve and control reactions by visual observation Distillation glass overhead built with buchiflex components (unique flexible ball - socket joints) for multiple, reliable processes under full vacuum Glass reactor:15, 30, 60 liter Pressure:-1.0 (FV) to +0.5 bar Temperature:-60 °C (-90 °C) to +200 °C Material:Borosilicate glass 3.3, glass-lined steel, PTFE, PFA, Tantalum